Artemis Therapeutics Announces Two Recent Publications Highlighting Artemisone’s Activity Against Human Cytomegalovirus And Malaria
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Preclinical Data Further Supports Potential For Treatment of HCMV and Malaria

SAN DIEGO, June 19, 2018 /PRNewswire/ — Artemis Therapeutics, Inc. (OTCQB: ATMS), (“Artemis” or the “Company”), a pharmaceutical company developing new therapies for the treatment of infectious diseases, including cytomegalovirus and malaria, today announced that data on its lead product candidate Artemisone have been published in two separate articles in the journal Antimicrobial Agents and Chemotherapy.  The studies indicate that Artemisone in a preclinical setting is a potent inhibitor of human cytomegalovirus (HCMV) replication and the transmissible stages of malaria.

“We are optimistic regarding the potential of Artemisone and the peer-reviewed publication of its activity in both CMV, a major cause of disease in immunocompromised individuals, such as stem cell and other transplant patients, and malaria, which is responsible for more than 400,000 deaths each year, is very encouraging,” said Brian Culley, CEO of Artemis. “Both conditions represent significant worldwide need, and each of these papers demonstrate the promise of Artemisone as a potential future therapy. We are actively working to advance both programs and hope to provide additional updates soon.”

The first paper, published online on June 4, demonstrates Artemisone’s inhibition of replication of an artemisinin-resistant strain of malaria in both intraerythrocytic proliferative asexual and transmissible gametocyte stages.  Authored by Richard K. Haynes, Ph.D., adjunct professor in the chemistry department at the Hong Kong University of Science and Technology and a research professor at the Centre of Excellence for Pharmaceutical Sciences at South Africa’s North-West University, the paper suggests that it is the capability of Artemisone to attack the disease particularly at the later gametocyte stages that provides significant differentiation from current modalities.

The second publication, authored by Dr. Dana Wolf, chief medical officer at Artemis Therapeutics, demonstrates Artemisone effectively inhibits laboratory-adapted and low-passage clinical strains of HCMV as well as drug-resistant HCMV strains. Further, its antiviral efficacy against HCMV is not only comparable to ganciclovir, but also approximately 10-fold greater than artesunate in all cell lines studied. The data indicates Artemisone is a reversible HCMV inhibitor, targeting an earlier phase of the viral replication cycle than does ganciclovir, suggesting a novel mechanism of action.

About Artemisone

Artemis’ lead product candidate, Artemisone (ar-tem-iss-ohn), is being developed as a best-in-class treatment for malaria and first-in-class treatment for CMV. Artemisone is a semi-synthetic 10-alpha-amino derivative of artemisinin, the discovery of which shared one-half of the 2015 Nobel Prize in Physiology or Medicine. Artemisone was selected as a therapeutic product candidate based on properties that distinguish it from other artemisinin derivatives, including greater potency, lower predicted neurotoxicity, better stability, half-life, and solubility. Notably, Artemisone relies on a non-DHA metabolic pathway, which distinguishes it from currently used artemisinins. This feature may provide important clinical advantages in terms of fighting resistance, blocking disease transmission, or treating severe and/or cerebral malaria. Additionally, recent laboratory research has shown that the antiviral potency of Artemisone against human cytomegalovirus (CMV) is as robust as the current FDA-approved agent, ganciclovir, and approximately ten times greater than that of a related compound, artesunate. Further in vitro studies with Artemisone have demonstrated efficacy against drug-resistant strains of CMV with evidence for a novel mechanism of action.

About Artemis Therapeutics

Artemis Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the development of new therapies for the treatment and prevention of severe and life-threatening infectious diseases. The Company’s lead product candidate, Artemisone, is a semi-synthetic artemisinin derivative with potent antiviral and antiparasitic properties. The Company currently is evaluating Artemisone for the treatment of P. falciparum malaria and human cytomegalovirus (CMV) infections, including stem cell transplant CMV, solid organ transplant CMV, and congenital CMV. Artemis also plans to evaluate Artemisone for the treatment of additional viral and parasitic diseases. More information is available on the Company’s website: www.artemis-therapeutics.com and Twitter: @ArtemisThera.

Forward Looking Statements:

This press release contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including those relating to the Company’s product development, clinical and regulatory timelines, market opportunity, competitive position, possible or assumed future results of operations, business strategies, potential growth opportunities and other statement that are predictive in nature. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management’s current beliefs and assumptions.

These statements may be identified by the use of forward-looking expressions, including, but not limited to, “expect,” “anticipate,” “intend,” “plan,” “believe,” “estimate,” “potential,” “predict,” “project,” “should,” “would” and similar expressions and the negatives of those terms. These statements relate to future events or our financial performance and involve known and unknown risks, uncertainties, and other factors which may cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Such factors include those set forth in the Company’s filings with the Securities and Exchange Commission. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.

Contact:
Investor Relations
(ir@artemis-therapeutics.com)

Media
Jules Abraham
JQA Partners, Inc.
jabraham@jqapartners.com
917-885-7378

 

SOURCE Artemis Therapeutics, Inc.

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Data Presented At The 31st International Conference For Antiviral Research Demonstrate Artemis Therapeutics’ Artemisone May Be An Effective Inhibitor Of Human CMV Replication
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SAN DIEGO, June 12, 2018 /PRNewswire/ — Artemis Therapeutics, Inc. (OTCQB: ATMS), (“Artemis” or the “Company”), a pharmaceutical company developing new therapies for the treatment of infectious diseases, including cytomegalovirus and malaria, today announced that new data on its lead product candidate, Artemisone, shows it is a potent inhibitor of human cytomegalovirus (HCMV) replication in preclinical assays, including a human placental tissue model. The company’s chief medical officer, Dana Wolf, M.D., Ph.D., will share the data in an oral presentation on June 14 during the 31st annual International Conference for Antiviral Research (ICAR) June 11-14 in Porto, Portugal.

“To have these new data accepted at two important international conferences within a short time underscores the interest in and urgent need for improved therapies for CMV and reflects positively on the potential of our drug candidate. The results we’ve seen in preclinical studies to date are encouraging, and we intend to advance Artemisone into the clinic for HCMV next year,” said Brian Culley, CEO of Artemis. “We are grateful to Dr. Wolf for ensuring these data are shared with multiple international audiences and look forward to reporting additional results soon.”

Dr. Wolf’s presentation will provide data that show Artemisone more effectively inhibits HCMV infection than ganciclovir in an ex vivo model of human placental tissues maintained in organ culture to mirror the maternal-fetal spread of virus in vivo. Artemisone recently has been reported to effectively inhibit laboratory-adapted and low-passage clinical strains of HCMV as well as drug-resistant HCMV strains. Further, its antiviral efficacy is not only comparable to ganciclovir, but also approximately 10-fold greater than artesunate in all cell lines studied. The data indicates Artemisone is a reversible HCMV inhibitor, targeting an earlier phase of the viral replication cycle than does ganciclovir, suggesting a novel mechanism of action.

The ICAR conference series aims to be a key forum for the presentation, exchange, and dissemination of information and experiences on anti-microbial strategies. It covers topics on antimicrobial resistance, detection, enhancement of innate defenses against pathogens, as well as various methods and techniques. The 31st annual congress will be held at the Alfândega Congress Centre in Porto, Portugal.

About Artemisone

Artemis’ lead product candidate, Artemisone (ar-tem-iss-ohn), is being developed as a best-in-class treatment for malaria and first-in-class treatment for CMV. Artemisone is a semi-synthetic 10-alpha-amino derivative of artemisinin, the discovery of which shared one-half of the 2015 Nobel Prize in Physiology or Medicine. Artemisone was selected as a therapeutic product candidate based on properties that distinguish it from other artemisinin derivatives, including greater potency, lower predicted neurotoxicity, better stability, half-life, and solubility. Notably, Artemisone relies on a non-DHA metabolic pathway, which distinguishes it from currently used artemisinins. This feature may provide important clinical advantages in terms of fighting resistance, blocking disease transmission, or treating severe and/or cerebral malaria. Additionally, recent laboratory research has shown that the antiviral potency of Artemisone against human cytomegalovirus (CMV) is as robust as the current FDA-approved agent, ganciclovir, and approximately ten times greater than that of a related compound, artesunate. Further in vitro studies with Artemisone have demonstrated efficacy against drug-resistant strains of CMV with evidence for a novel mechanism of action.

About Artemis Therapeutics

Artemis Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the development of new therapies for the treatment and prevention of severe and life-threatening infectious diseases. The Company’s lead product candidate, Artemisone, is a semi-synthetic artemisinin derivative with potent antiviral and antiparasitic properties. The Company currently is evaluating Artemisone for the treatment of P. falciparum malaria and human cytomegalovirus (CMV) infections, including stem cell transplant CMV, solid organ transplant CMV, and congenital CMV. Artemis also plans to evaluate Artemisone for the treatment of additional viral and parasitic diseases. More information is available on the Company’s website: www.artemis-therapeutics.com and Twitter: @ArtemisThera.

Forward Looking Statements:

This press release contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including those relating to the Company’s product development, clinical and regulatory timelines, market opportunity, competitive position, possible or assumed future results of operations, business strategies, potential growth opportunities and other statement that are predictive in nature. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management’s current beliefs and assumptions.

These statements may be identified by the use of forward-looking expressions, including, but not limited to, “expect,” “anticipate,” “intend,” “plan,” “believe,” “estimate,” “potential,” “predict,” “project,” “should,” “would” and similar expressions and the negatives of those terms. These statements relate to future events or our financial performance and involve known and unknown risks, uncertainties, and other factors which may cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Such factors include those set forth in the Company’s filings with the Securities and Exchange Commission. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.

Contact:
Investor Relations
(ir@artemis-therapeutics.com)

Media
Jules Abraham
JQA Partners, Inc.
jabraham@jqapartners.com
917-885-7378

SOURCE Artemis Therapeutics, Inc.

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New Data Demonstrate Artemis Therapeutics’ Artemisone May Be An Effective Inhibitor Of Human CMV Replication
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SAN DIEGO, June 7, 2018 /PRNewswire/ — Artemis Therapeutics, Inc. (OTCQB: ATMS), (“Artemis” or the “Company”), a pharmaceutical company developing new therapies for the treatment of infectious diseases, including cytomegalovirus and malaria, today announced that new data on its lead product candidate Artemisone shows it is a potent inhibitor of human cytomegalovirus (HCMV) replication in preclinical assays.  The company’s chief medical officer, Dana Wolf, M.D., Ph.D., will share the data in an oral presentation on June 9th at the American Society of Microbiology annual meeting in Atlanta (ASM Microbe 2018), as part of Session 305, CMV Resistance: Limited Options but a Promising Future.

“CMV is a major cause of disease in immunocompromised individuals, such as stem cell and other transplant patients. The combination of a growing patient population and the limitations of existing antiviral treatments underscore the need for new antiviral agents with alternative modes of action,” said Brian Culley, CEO of Artemis. “While we previously have shown Artemisone’s potential against malaria in a clinical setting, this is our first presentation at a scientific meeting of Artemisone’s potential to work against HCMV and the preclinical results are highly promising. We are honored for Dr. Wolf to be presenting these data at the ASM meeting and look forward to moving this program into the clinic next year and reporting additional results soon.”

Dr. Wolf’s presentation will provide data that shows Artemisone effectively inhibits laboratory-adapted and low-passage clinical strains of HCMV as well as drug-resistant HCMV strains. Further, its antiviral efficacy is not only comparable to ganciclovir, but also approximately 10-fold greater than artesunate in all cell lines studied. The data indicates Artemisone is a reversible HCMV inhibitor, targeting an earlier phase of the viral replication cycle than does ganciclovir, suggesting a novel mechanism of action.

A peer-reviewed publication of the new data is forthcoming.

ASM Microbe 2018 is an annual meeting which connects scientists with their science, showcases the best microbial sciences in the world, and provides a one-of-a-kind forum to explore the complete spectrum of microbiology from basic science to translation and application. Interested parties may follow @ASMicrobiology on Twitter and use #ASMicrobe for the latest meeting updates. Additional information on the meeting can be found here.

About Artemisone

Artemis’ lead product candidate, Artemisone (ar-tem-iss-ohn), is being developed as a best-in-class treatment for malaria and first-in-class treatment for CMV. Artemisone is a semi-synthetic 10-alpha-amino derivative of artemisinin, the discovery of which shared one-half of the 2015 Nobel Prize in Physiology or Medicine. Artemisone was selected as a therapeutic product candidate based on properties that distinguish it from other artemisinin derivatives, including greater potency, lower predicted neurotoxicity, better stability, half-life, and solubility. Notably, Artemisone relies on a non-DHA metabolic pathway, which distinguishes it from currently used artemisinins. This feature may provide important clinical advantages in terms of fighting resistance, blocking disease transmission, or treating severe and/or cerebral malaria. Additionally, recent laboratory research has shown that the antiviral potency of Artemisone against human cytomegalovirus (CMV) is as robust as the current FDA-approved agent, ganciclovir, and approximately ten times greater than that of a related compound, artesunate. Further in vitro studies with Artemisone have demonstrated efficacy against drug-resistant strains of CMV with evidence for a novel mechanism of action.

About Artemis Therapeutics

Artemis Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the development of new therapies for the treatment and prevention of severe and life-threatening infectious diseases. The Company’s lead product candidate, Artemisone, is a semi-synthetic artemisinin derivative with potent antiviral and antiparasitic properties. The Company currently is evaluating Artemisone for the treatment of P. falciparum malaria and human cytomegalovirus (CMV) infections, including stem cell transplant CMV, solid organ transplant CMV, and congenital CMV. Artemis also plans to evaluate Artemisone for the treatment of additional viral and parasitic diseases. More information is available on the Company’s website: www.artemis-therapeutics.com and Twitter: @ArtemisThera.

Forward Looking Statements:

This press release contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including those relating to the Company’s product development, clinical and regulatory timelines, market opportunity, competitive position, possible or assumed future results of operations, business strategies, potential growth opportunities and other statement that are predictive in nature. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management’s current beliefs and assumptions.

These statements may be identified by the use of forward-looking expressions, including, but not limited to, “expect,” “anticipate,” “intend,” “plan,” “believe,” “estimate,” “potential,” “predict,” “project,” “should,” “would” and similar expressions and the negatives of those terms. These statements relate to future events or our financial performance and involve known and unknown risks, uncertainties, and other factors which may cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Such factors include those set forth in the Company’s filings with the Securities and Exchange Commission. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.

Contact:
Investor Relations
(ir@artemis-therapeutics.com)

Media
Jules Abraham
JQA Partners, Inc.
jabraham@jqapartners.com
917-885-7378

Artemis Therapeutics Announces Additional Patent Issuance For Artemisone For The Treatment Of Viral Infections
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SAN DIEGO, April 16, 2018 /PRNewswire/ — Artemis Therapeutics, Inc. (OTCQB: ATMS), (“Artemis” or the “Company”), a pharmaceutical company developing new therapies for the treatment of life-threatening infectious diseases, today announced the decision by the Japanese Patent Office to allow the patent entitled “Methods and Compositions for Treating Viral Infections”. The patent covers certain compositions, including Artemisone, the Company’s lead product candidate, for use in treating or suppressing herpesvirus infection and replication. Artemisone is a novel agent currently under investigation as an antiviral for the treatment of cytomegalovirus (CMV) and as an antiparasitic for the treatment of P. falciparum malaria. The patent will provide intellectual property protection for the Artemisone program in Japan and is expected to expire no earlier than April, 2033.

“The issuance of this Japanese patent is a significant third pillar of our worldwide market protection strategy and augments our existing intellectual property protection in the U.S. and Europe, where our patents for Artemisone were allowed last year,” stated Brian M. Culley, Chief Executive Officer of Artemis. “We believe Artemisone has potential across a broad range of human diseases and we plan to publish data on Artemisone’s activity against CMV around the middle of this year. Meanwhile, the issuance of this patent will provide protection and strengthen commercial opportunities for the development of the program beyond malaria and CMV and into other viral infectious diseases.”

CMV is a common infection in Japan. In addition to individuals with weakened immunity, including post-transplantation and HIV patients, CMV also may reactivate in inflammatory bowel diseases such as colitis. Newborns may become infected by their mothers, leading to asymptomatic or symptomatic manifestations of the disease. According to a 2018 publication from the Japanese Congenital Cytomegalovirus study group, the rate of late-onset sequelae observed in Japan is similar to that reported in the USA and Europe. Additionally, the treatment of symptomatic patients with antiviral agents results in favorable clinical outcomes.

About Artemis Therapeutics
Artemis Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the development of new therapies for the treatment and prevention of severe and life-threatening infectious diseases. The Company’s lead product candidate, Artemisone, was originally developed by Bayer HeathCare AG. Artemisone is a unique, synthetic artemisinin derivative with potent antiviral and antiparasitic properties. The Company currently is evaluating Artemisone for the treatment of P. falciparum malaria and human cytomegalovirus (CMV) infections, including stem cell transplant CMV and congenital CMV. Artemis also plans to evaluate Artemisone for the treatment of additional viral and parasitic diseases. More information is available on the Company’s website: www.artemis-therapeutics.com and Twitter: @ArtemisThera.

Forward Looking Statements:
This press release contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including those relating to the Company’s product development, clinical and regulatory timelines, market opportunity, competitive position, possible or assumed future results of operations, business strategies, potential growth opportunities and other statement that are predictive in nature. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management’s current beliefs and assumptions.

These statements may be identified by the use of forward-looking expressions, including, but not limited to, “expect,” “anticipate,” “intend,” “plan,” “believe,” “estimate,” “potential,” “predict,” “project,” “should,” “would” and similar expressions and the negatives of those terms. These statements relate to future events or our financial performance and involve known and unknown risks, uncertainties, and other factors which may cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Such factors include those set forth in the Company’s filings with the Securities and Exchange Commission. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.

Contact:                                                                     

Investor Relations
(ir@artemis-therapeutics.com)

 

SOURCE Artemis Therapeutics, Inc.

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Artemis Therapeutics Announces Issuance Of European Patent For Artemisone For The Treatment Of Viral Infections
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NEW YORK, Nov. 28, 2017 /PRNewswire/ — Artemis Therapeutics, Inc. (OTCQB: ATMS), (“Artemis” or the “Company”), a pharmaceutical company developing new therapies to treat life-threatening infectious diseases, today announced the recent issuance by the European Patent Office (EPO) of European Patent No. 2839803 entitled “Methods and Compositions for Treating Viral Infections” covering the Company’s lead product candidate, Artemisone, currently in development for the treatment of malaria and cytomegalovirus (CMV). The European patent will provide intellectual property protection for the Artemisone program in key markets and is expected to expire no earlier than 2033.

“The issuance of this European patent is a significant component of our worldwide intellectual property strategy and augments our existing intellectual property assets such as U.S. patent 9,616,067, ‘Methods and Compositions for Treating Viral Infections’, which was allowed in April of this year,” stated Brian M. Culley, Chief Executive Officer of Artemis. “We believe Artemisone has potential across a broad range of human diseases and the issuance of this patent will provide protection as well as strengthen the commercial opportunities for the development of the program beyond malaria and CMV and into additional viral infectious diseases. We look forward to providing information about those additional indications for Artemisone in the coming months.”

About Artemis Therapeutics

Artemis Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the development of new therapies for the treatment and prevention of severe and life-threatening infectious diseases. The Company’s lead product candidate, Artemisone, is a unique, synthetic artemisinin derivative with potent anti-viral and anti-parasitic properties. The Company currently is evaluating Artemisone for the treatment of p. falciparum malaria and human cytomegalovirus (CMV) infections, including stem cell transplant CMV and congenital CMV. Artemis also plans to evaluate Artemisone for the treatment of additional viral and parasitic diseases. More information is available on the Company’s website: www.artemis-therapeutics.com and Twitter: @ArtemisThera.

Forward Looking Statements:

This press release contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including those relating to the Company’s product development, clinical and regulatory timelines, market opportunity, competitive position, possible or assumed future results of operations, business strategies, potential growth opportunities and other statement that are predictive in nature. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management’s current beliefs and assumptions.

These statements may be identified by the use of forward-looking expressions, including, but not limited to, “expect,” “anticipate,” “intend,” “plan,” “believe,” “estimate,” “potential,” “predict,” “project,” “should,” “would” and similar expressions and the negatives of those terms. These statements relate to future events or our financial performance and involve known and unknown risks, uncertainties, and other factors which may cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Such factors include those set forth in the Company’s filings with the Securities and Exchange Commission. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.

Contact: 

Investor Relations
(ir@artemis-therapeutics.com)

SOURCE Artemis Therapeutics, Inc.

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Artemis Therapeutics Receives Orphan Drug Designation From U.S. Food And Drug Administration For Artemisone For The Treatment Of Malaria
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NEW YORK, Nov. 6, 2017 /PRNewswire/ — Artemis Therapeutics, Inc. (OTCQB: ATMS), (“Artemis” or the “Company”), a pharmaceutical company developing new therapies for the treatment of life-threatening infectious diseases, today announced that the U.S. Food and Drug Administration (FDA) granted orphan drug designation for Artemisone, the Company’s lead product candidate, for the treatment of malaria.

“We are delighted Artemisone has received orphan drug designation from the FDA for the treatment of malaria,” stated Brian M. Culley, Chief Executive Officer of Artemis. “With approximately half of the world’s population at risk, malaria presents an unmet global challenge with enormous economic implications. In recent years, artemisinin-resistant malaria has become increasingly common. Our product candidate, Artemisone, is a potent and fast-acting member of the artemisinin class and we believe it may offer a more attractive safety and efficacy profile compared to currently-available artemisinins. We are excited to be moving Artemisone toward additional clinical trials.”

The FDA Orphan Drug designation program provides incentives to sponsors that are developing therapies for rare diseases which affect fewer than 200,000 people in the United States. Artemis is now qualified to receive significant benefits throughout its orphan drug development program including more frequent FDA interactions, protocol assistance, and tax credits for clinical research costs. Also included is a waiver of certain fees and a seven-year term of market exclusivity upon FDA approval of the orphan drug. In 2015, malaria caused 212 million clinical episodes and 429,000 deaths, according to the World Health Organization.

About Artemis Therapeutics

Artemis Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the development of new therapies for the treatment and prevention of severe and life-threatening infectious diseases. The Company’s lead product candidate, Artemisone, is a unique, synthetic artemisinin derivative with potent anti-viral and anti-parasitic properties. The Company currently is evaluating Artemisone for the treatment of p. falciparum malaria and human cytomegalovirus (CMV) infections, including stem cell transplant CMV and congenital CMV. Artemis also plans to evaluate Artemisone for the treatment of additional viral and parasitic diseases. More information is available on the Company’s website: www.artemis-therapeutics.com and Twitter: @ArtemisThera.

Forward Looking Statements:

This press release contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including those relating to the Company’s product development, clinical and regulatory timelines, market opportunity, competitive position, possible or assumed future results of operations, business strategies, potential growth opportunities and other statement that are predictive in nature. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management’s current beliefs and assumptions.

These statements may be identified by the use of forward-looking expressions, including, but not limited to, “expect,” “anticipate,” “intend,” “plan,” “believe,” “estimate,” “potential,” “predict,” “project,” “should,” “would” and similar expressions and the negatives of those terms. These statements relate to future events or our financial performance and involve known and unknown risks, uncertainties, and other factors which may cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Such factors include those set forth in the Company’s filings with the Securities and Exchange Commission. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.

Contact:

Investor Relations
(ir@artemis-therapeutics.com)

SOURCE Artemis Therapeutics, Inc.

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